Not really, and it may not really be possible in some sense anyway because, technically, NPC do not have to meet the same rule requirements as PCs (as is mentioned with some regularity on the Pinnacle forums.) Now Archetypes SHOULD follow the rules, but they don't necessarily always do so. Mostly, though, Advances shouldn't throw you too many loops and I wouldn't call that a Supers issue anyway (since Advances are going to happen after all Super Power Points get spent, except in the rarer instance when using something like the "Rising Stars" setting rule, which personally I don't recommend using anyway having played several campaigns with and without that setting rule.) While it is true that some Advances can affect some super powers (most notably Super Attribute and Super Skill) overall the Advances shouldn't throw you too big of a loop trying to figure out.
Probably the best place to ask about that would be the Pinnacle forums, though, or on the forums for the sourcebook you are getting your NPCs from, with which NPCs in particular you are running into issues with. Lots of helpful and experienced folks who may be able to help walk you through a few of the examples, or you could try starting a new thread here (I wouldn't use this one since, IMHO, it's really more for specific questions or issues with the new SPC2 data file update rather than more generic questions like that.)