Follow along with the video below to see how to install our site as a web app on your home screen.
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On the Personal tab, in the Permanent Adjustments table, choose the "Advancement Karma Cost" adjustment, and you can use that to select one of your advancements and change its cost.
You're being vague about what you want to change the cost of - could you please be more specific about what you're trying to implement?
In the Develop menu, make sure "Enable Data File Debugging" is turned on. Then, at the bottom of the develop menu, choose floating info windows...show selection fields. In that list, use the search terms "mechBP" and mechKa", and then select the version of those that aren't labeled "Fin" (which are the final versions - you want to modify the initial version instead).
Among all those field values, you'll find where most of the karma costs are stored. You'll be writing scripts to change them, and you'll want to make your changes before Initialize/15000 (so Initialize/10000 is probably a good time to make them).
I'm afraid I'm leaving for Gen Con tomorrow, so I won't have time to give you a more detailed how to until I get back, so I'm sorry about that.