[Parody]

I don't know DevExpress, but one thing you could try (if it lets you) is disabling font previews in the font selection combo boxes. The hope is that they then delay loading each font until it's actually used and just rely on the list of names provided by the system for selecting fonts. If most of us are using the defaults then Realm Works would only need the Tahoma variants, cutting potentially hundreds of loaded fonts down to four.

Edit: Actually two; Tahoma doesn't come with italics.