Imho, removing Fonts from the system is not a very viable option. I have two reasons this is not good (at least for me); 1: Windows won't let me (may be policy rules), 2: I need a lot of fonts for my professional and private work.
One option would be to load only the necessary fonts into the RW runtime, but by using 3rd party librarys like DevExpress you might not be able to control that, but that sounds weird to me as a .NET developer.
Have you explored the various UI improvements that DevExpress offers? The UI could (in the far future when you have time) benefit from some upgrades to a more modern UI
Is there any work on moving RW to 64-bit?