There's also the Hero Lab command line option "-dataroot e:\path\to\data\". See the Miscellaneous Details link in the Hero Lab manual. (It's in the Help menu once you pick a game system.)
I use that on my main machine (via a shortcut that also opens the Pathfinder system on startup), and I've also gone in and fixed the registry entries so I can open portfolio files from the file system.
(It should really be a preference, though. :(
|