tahltwo - the handwraps of mighty fists allow runes and item quality, but I see nothing in their rules that allows them to make use of weapon trinkets.
In the trinket rules on pg. 379, it says that they are affixed "...to armor, a shield, or a weapon..." The handwrap of mighty fists is not a weapon by itself, it is a magic item, and I don't think that the intent is that a chracter's fists or other unarmed strikes by themselves count as a weapon for the purpose of having trinkets attached.
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