The integration (looking at the current version of Syrinscape) lets you create a link that is like clicking a button in the Syrinscape application. So while it works a little quirky behind the scenes (described below), at a minimum all LWD has to do is allow the Syrinscape URI schemes and it would work. (If I were using it, though, I'd hope for something with a button.)
The way Syrinscape implemented it is based on a custom URI scheme and a watched folder. Here's a sample link:
Code:
syrinscape-fantasy:moods/d2l0Y2h3b29kOjpSYWluaW5nIGFnYWlu/play/
If you have Syrinscape Fantasy Player installed and you pasted that into Internet Explorer, IE would (after a bunch of warning dialogs) fire up an application that removes the scheme, writes the rest to a temp file in a watched folder, and starts Syrinscape Fantasy. The Syrinscape app then reads that file, starts the linked asset, and deletes the temp file.
You could sidestep it if you wanted, but since you can't identify anything by name anyway (you can't say 'play "set=Witchwood" item="Raining Again"' or "syrinscape-fantasy:play//Witchwood/Raining%20Again/") you might as well let their app write the file for you.