Realm Works w/ HERO System
 

I am working on a campaign for Fantasy Hero, from the looks of it, I won't be able to use Hero Lab and will have to use Hero Designer v6.

Does this mean that I will be limited in the functionality I will be able to access via Realm Works?

The only limitation you'll encounter is that the Hero Designer tool won't be as closely integrated into Realm Works as Hero Lab. If the developers of HD want to provide the same level of integration once RW is released, they can, but it will entail some extra work to incorporate the additional integration features. The net effect of lesser integration will be a few extra steps when dealing with character profiles. That's the only drawback you'll encounter.